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    Ingredient Database

    276 evidence-based supplement ingredients indexed · 776 studies across 18 categories

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    276 ingredients found

    Creatine Monohydrate

    Ergogenic Compounds
    94/100

    Creatine monohydrate is one of the most well-researched and effective sports nutrition supplements available. It has been shown to increase strength, power output, and lean body mass across hundreds of human clinical trials.

    Strength trainingPower sportsCognitive support
    5 studies2linked products2trademarked versions
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    Ashwagandha

    Adaptogens
    82/100

    Ashwagandha (Withania somnifera) is a premier adaptogenic herb used for centuries in Ayurvedic medicine. Modern clinical research supports its role in reducing cortisol, improving stress resilience, and supporting hormonal balance.

    Stress managementSleep qualityHormonal balance
    3 studies1linked products2trademarked versions
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    Vitamin D3

    Vitamins
    91/100

    Vitamin D3 (cholecalciferol) is a fat-soluble secosteroid essential for calcium absorption, bone mineralization, immune regulation, and neuromuscular function. Deficiency is highly prevalent globally.

    Bone healthImmune functionMood regulation
    3 studies1linked products
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    Beta-Alanine

    Amino Acids
    78/100

    Beta-alanine is a non-essential amino acid that increases intramuscular carnosine concentrations. It is most effective for exercise lasting 1–10 minutes.

    High-intensity exerciseEndurance sportsCrossFit
    3 studies1trademarked versions
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    L-Theanine

    Nootropics
    72/100

    L-Theanine is an amino acid found primarily in green tea. It promotes relaxation without drowsiness and synergizes with caffeine to enhance focus and attention.

    Focus enhancementRelaxationSleep onset
    3 studies1trademarked versions
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    Magnesium Glycinate

    Minerals
    84/100

    Magnesium glycinate is a highly bioavailable form of magnesium chelated with glycine. It is favored for sleep support and muscle recovery due to excellent absorption and tolerability.

    Sleep supportMuscle recoveryStress management
    3 studies1linked products1trademarked versions
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    Lactobacillus Rhamnosus GG

    Digestive Enzymes, Probiotics & Fibers
    80/100

    One of the most extensively studied probiotic strains globally. LGG has strong evidence for preventing antibiotic-associated diarrhea, supporting immune function, and improving gut barrier integrity.

    Gut healthImmune supportAntibiotic recovery
    2 studies
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    Digestive Enzyme Complex

    Digestive Enzymes, Probiotics & Fibers
    58/100

    Digestive enzyme supplements contain proteases, amylases, and lipases that assist in the breakdown of macronutrients. They are particularly useful for individuals with pancreatic insufficiency or age-related enzyme decline.

    Protein digestionBloating reliefNutrient absorption
    1 study1trademarked versions
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    Sodium Citrate

    Hydration Ingredients
    65/100

    Sodium citrate is a buffering electrolyte salt used in hydration formulas and as an ergogenic alkalizing agent. It replenishes sodium lost through sweat and may buffer metabolic acidosis during high-intensity exercise.

    Electrolyte replenishmentEndurance sportsHeat acclimatization
    1 study
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    Coconut Water Powder

    Hydration Ingredients
    48/100

    Coconut water powder is a dehydrated form of coconut water providing a natural source of potassium, sodium, magnesium, and other electrolytes. It offers a whole-food alternative to synthetic electrolyte formulas.

    Natural hydrationElectrolyte replenishmentPost-exercise recovery
    1 study
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    Collagen Peptides

    Joint and Recovery Ingredients
    70/100

    Collagen peptides are enzymatically hydrolyzed collagen proteins providing bioactive peptides that stimulate fibroblast activity and support connective tissue synthesis throughout the body.

    Joint healthTendon recoverySkin elasticity
    3 studies1linked products2trademarked versions
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    Glucosamine Sulfate

    Joint and Recovery Ingredients
    62/100

    Glucosamine sulfate is an amino sugar and precursor to glycosaminoglycans (GAGs), the primary structural components of cartilage. It is one of the most widely used joint health supplements globally.

    OsteoarthritisJoint painCartilage support
    1 study1trademarked versions
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    Tart Cherry Extract

    Joint and Recovery Ingredients
    58/100

    Tart cherry extract from Montmorency cherries is rich in anthocyanins and natural melatonin. It has emerging evidence for reducing exercise-induced muscle damage, improving sleep quality, and lowering uric acid levels.

    Muscle recoverySleep supportInflammation
    3 studies1trademarked versions
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    Tongkat Ali

    Hormonal Support Ingredients
    55/100

    Tongkat Ali (Eurycoma longifolia) is a Southeast Asian medicinal plant with growing clinical evidence for supporting healthy testosterone levels, reducing cortisol, and improving male reproductive health parameters.

    Testosterone supportLibido enhancementStress resilience
    2 studies1trademarked versions
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    Apigenin

    Sleep and Stress Support Ingredients
    42/100

    Apigenin (4',5,7-trihydroxyflavone) is a dietary flavone abundant in chamomile (Matricaria chamomilla), parsley, celery, and thyme. It is best known as a natural sleep aid via GABA-A benzodiazepine-site modulation and has emerged as a CD38 inhibitor that helps preserve cellular NAD+. Popularized by Andrew Huberman as part of a sleep stack, isolated apigenin has strong mechanistic data but no published RCTs in humans — all clinical evidence to date uses chamomile extracts standardized to apigenin.

    Sleep onsetAnxiety reductionCellular NAD+ support
    15 studies3linked products2trademarked versions
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    Berberine

    Metabolic Health Ingredients
    76/100

    Berberine is an isoquinoline alkaloid found in goldenseal, barberry, and Oregon grape. It has remarkable clinical evidence for glucose and lipid metabolism — often compared to metformin in head-to-head trials.

    Blood sugar managementCholesterol supportMetabolic syndrome
    2 studies1trademarked versions
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    L-Citrulline

    Pump and Performance Ingredients
    74/100

    L-Citrulline is a non-essential amino acid that serves as the most effective oral precursor to nitric oxide (NO) production. It bypasses hepatic first-pass metabolism better than L-arginine, making it superior for raising plasma arginine and NO levels.

    Pre-workout vasodilationEndurance performanceBlood pressure support
    3 studies1trademarked versions
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    Nitrosigine®

    Pump and Performance Ingredients
    82/100

    Nitrosigine® is a patented complex of bonded arginine silicate stabilized with inositol (ASI). It delivers a uniquely sustained and clinically superior elevation of plasma arginine and silicon levels compared to standard arginine, producing both vascular and cognitive performance benefits within a single 1500mg dose.

    Nitric oxide enhancementPre-workout vasodilationCognitive focus during training
    4 studies4linked products1trademarked versions
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    Betaine Anhydrous

    Pump and Performance Ingredients
    74/100

    Betaine Anhydrous (trimethylglycine) is a naturally occurring osmolyte and methyl donor with dual roles in performance and metabolic health. As an osmolyte, it protects cells from dehydration stress. As a methyl donor, it supports creatine synthesis and homocysteine recycling. Clinical trials show improvements in power output, work capacity, and body composition.

    Power outputBody compositionOsmolyte cell hydration
    3 studies3linked products1trademarked versions
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    Glycerol

    Pump and Performance Ingredients
    70/100

    Glycerol is a trihydric sugar alcohol that induces cellular hyperhydration by acting as an osmotic agent in body water compartments. It draws and retains fluid in muscle tissue and plasma, producing dramatic muscle fullness, improved thermoregulation, and enhanced endurance performance — particularly in hot environments. Modern high-yield powder forms like GlycerSize™ and HydroMax® deliver 65% glycerol content, solving the clumping issues of older glycerol monostearate products.

    HyperhydrationMuscle volumizationEndurance in heat
    2 studies3linked products2trademarked versions
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    S7™

    Pump and Performance Ingredients
    64/100

    S7™ is a clinically studied, low-dose (50mg) blend of seven plant-based ingredients that increases the body's own nitric oxide production by 230%. Unlike arginine or citrulline which provide NO precursors, S7™ works by upregulating endogenous eNOS enzyme activity — triggering the body to produce more NO from its own pathways.

    Endogenous NO productionPlant-based pumpLow-dose vasodilation
    3 studies3linked products1trademarked versions
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    Agmatine Sulfate

    Pump and Performance Ingredients
    58/100

    Agmatine Sulfate is a metabolite of L-arginine produced by decarboxylation via arginine decarboxylase (ADC). It functions as a neuromodulator and NO regulator with a unique mechanism — it inhibits the arginase enzyme that breaks down arginine, thereby extending the half-life of circulating arginine and prolonging NO-mediated vasodilation. It also acts on imidazoline, alpha-2 adrenergic, and NMDA receptors for neuroprotective and mood-regulating effects.

    Nitric oxide modulationPump enhancementNeuroprotection
    2 studies2linked products1trademarked versions
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    Beetroot Extract

    Pump and Performance Ingredients
    80/100

    Beetroot Extract provides concentrated dietary nitrate (NO₃⁻) that is converted to nitric oxide through the nitrate-nitrite-NO pathway — a completely separate and complementary pathway to the arginine-eNOS route used by citrulline and Nitrosigine. This dual-pathway NO production makes beetroot a unique and evidence-backed endurance and pump ingredient.

    Endurance performanceNatural NO productionBlood pressure support
    3 studies3linked products3trademarked versions
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    Alpha-GPC

    Nootropics
    78/100

    Alpha-GPC is the most bioavailable choline source, rapidly crossing the blood-brain barrier to serve as a precursor for acetylcholine synthesis. It supports both cognitive function and physical performance by enhancing neuromuscular signaling.

    Cognitive enhancementMemory supportPower output
    2 studies2linked products1trademarked versions
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