Ingredient Database

L-Theanine is an amino acid found primarily in green tea. It promotes relaxation without drowsiness and synergizes with caffeine to enhance focus and attention.

Alpha-GPC is the most bioavailable choline source, rapidly crossing the blood-brain barrier to serve as a precursor for acetylcholine synthesis. It supports both cognitive function and physical performance by enhancing neuromuscular signaling.

Lion's Mane is a medicinal mushroom with unique neurotrophic properties. It contains hericenones and erinacines that stimulate Nerve Growth Factor (NGF) synthesis, supporting neuroplasticity, memory, and nerve regeneration.

Caffeine anhydrous is the most extensively studied ergogenic aid, antagonising adenosine receptors to reduce perceived effort and improve endurance, strength, and cognitive performance.

Infinergy is caffeine ionically bonded to malic acid (~75% caffeine by mass), marketed for slightly slower absorption, reduced GI upset, and a smoother energy curve than caffeine anhydrous.

Theacrine is a purine alkaloid structurally related to caffeine that produces stimulant-like effects with reduced tolerance development over time.

Phenylethylamine (PEA) is a trace amine and rapid-onset mood/focus enhancer that triggers catecholamine release; oral effects are very short-lived due to rapid MAO-B metabolism.

Huperzine A is a potent, selective, reversible acetylcholinesterase inhibitor isolated from Chinese club moss, used for memory support and as a cognitive enhancer.

Bacopa monnieri is an Ayurvedic herb standardised for bacosides. It is one of the better-studied herbal nootropics, with several human trials suggesting benefits for memory acquisition and retention after weeks of consistent use.

Ginkgo biloba leaf extract, standardised to 24% flavone glycosides and 6% terpene lactones (the '24/6' standard), is one of the most studied herbal extracts. Large trials in healthy older adults have not shown prevention of cognitive decline; smaller studies suggest modest effects in existing impairment.

Citicoline (CDP-choline) is a choline donor and uridine precursor that supports phosphatidylcholine synthesis in neuronal membranes. It has a substantial clinical history in stroke and cognitive impairment in some countries, and is a popular nootropic-stack ingredient.

Phosphatidylserine is a phospholipid concentrated in neuronal membranes. Modern supplements are soy- or sunflower-derived (the original bovine cortex form is no longer used). Human studies suggest modest cognitive benefits in older adults and possible cortisol blunting during exercise stress.

Acetyl-L-carnitine (ALC) is an acetylated form of carnitine used as an oral nutraceutical for cognitive symptoms, neuropathic pain, and liver-related encephalopathy. Clinical evidence from systematic reviews and guidelines is mixed: some older dementia trials suggested benefit while later, larger trials were not supportive, and guidance warns against use in chemotherapy-induced peripheral neuropathy.

Anserine is a histidine-containing dipeptide found in muscle and brain tissue and is available in dietary supplements, often together with carnosine. Randomized controlled trials report modest preservation of delayed verbal memory and some protection against cognitive decline in older adults and people with mild cognitive impairment.