Skip to content

    Ingredient Database

    276 evidence-based supplement ingredients indexed · 776 studies across 18 categories

    Search and filter ingredients

    Search by effect / purpose: Browse manufacturers

    Ingredient results

    276 ingredients found

    VitaActives

    33 ingredients

    Digestive Enzyme Complex

    Digestive Enzymes, Probiotics & Fibers
    58/100

    Digestive enzyme supplements contain proteases, amylases, and lipases that assist in the breakdown of macronutrients. They are particularly useful for individuals with pancreatic insufficiency or age-related enzyme decline.

    Protein digestionBloating reliefNutrient absorption
    1 study1trademarked versions
    View

    Curcumin

    Botanical Extracts
    85/100

    Curcumin is the principal curcuminoid of turmeric (Curcuma longa), with potent anti-inflammatory and antioxidant properties rivaling pharmaceutical agents in some clinical comparisons. Its major limitation — poor native bioavailability — is overcome by enhanced formulations.

    Anti-inflammationJoint supportAntioxidant defense
    2 studies2linked products4trademarked versions
    View

    Piperine

    General Health Ingredients
    82/100

    Piperine is the primary pungent alkaloid found in black pepper (Piper nigrum) and long pepper (Piper longum). It is the most widely studied and utilized natural bioenhancer, dramatically increasing the absorption and bioavailability of a vast range of co-administered nutrients, vitamins, and supplement ingredients through multiple complementary mechanisms.

    Bioavailability enhancementNutrient absorptionThermogenesis
    4 studies8linked products3trademarked versions
    View

    Vitamin B9 (L-Methylfolate / 5-MTHF)

    Vitamins
    75/100

    L-Methylfolate (5-MTHF) is the biologically active, methylated form of folate (Vitamin B9). Unlike synthetic folic acid, 5-MTHF does not require enzymatic conversion by the dihydrofolate reductase (DHFR) enzyme, making it directly usable by the body. This is particularly relevant for individuals with genetic polymorphisms (e.g., MTHFR) that impair folic acid metabolism. Folate is essential for numerous physiological processes, including DNA synthesis and repair, methylation reactions, and the metabolism of homocysteine.

    Mood supportCardiovascular healthCognitive function
    4 studies1trademarked versions
    View

    Vitamin K2 (MK-7)

    Vitamins
    75/100

    Vitamin K2, specifically menaquinone-7 (MK-7), is a fat-soluble vitamin crucial for activating proteins involved in blood clotting, bone metabolism, and vascular health. Unlike Vitamin K1 (phylloquinone), which is primarily found in leafy green vegetables and is essential for coagulation, MK-7 has a longer half-life and plays a more significant role in extrahepatic tissues, particularly in bone and arteries.

    Bone HealthCardiovascular HealthCalcium Metabolism
    4 studies1trademarked versions
    View

    Caffeine Anhydrous

    Nootropics
    90/100

    Caffeine anhydrous is the most extensively studied ergogenic aid, antagonising adenosine receptors to reduce perceived effort and improve endurance, strength, and cognitive performance.

    EnergyFocusEndurance performance
    1 study1trademarked versions
    View

    Grapeseed Extract

    Botanical Extracts
    62/100

    Grapeseed extract is rich in oligomeric proanthocyanidins (OPCs) supporting vascular health, antioxidant defence, and modest blood pressure reduction.

    Vascular healthAntioxidantBlood pressure support
    1 study1trademarked versions
    View

    Chromium Picolinate

    Minerals
    58/100

    Chromium picolinate is a bioavailable form of trivalent chromium that supports insulin action and may modestly reduce carbohydrate cravings.

    Glucose supportCravingsBody composition
    1 study1trademarked versions
    View

    CoQ10

    General Health Ingredients
    78/100

    Coenzyme Q10 (ubiquinone) is a mitochondrial electron carrier and lipophilic antioxidant; supplementation supports energy production, heart health, and counters statin-induced depletion.

    Mitochondrial functionCardiovascular healthEnergy
    1 study1trademarked versions
    View

    Trans-Resveratrol

    Novel and Emerging Ingredients
    62/100

    Trans-resveratrol is a polyphenol from grapes and Japanese knotweed that activates SIRT1, supports cardiovascular function, and has shown longevity benefits in preclinical models.

    Sirtuin activatorCardiovascular healthLongevity
    1 study1trademarked versions
    View

    Garcinia Cambogia

    Metabolic Health Ingredients
    25/100

    Garcinia cambogia is a tropical fruit whose rind yields hydroxycitric acid (HCA), typically standardised to 50–60%. It has been marketed for weight management for decades, though the human evidence for meaningful fat loss is weak and inconsistent.

    Weight-management formulasAppetite-support blendsMetabolic health products
    0 studies1trademarked versions
    View

    Hyaluronic Acid

    Joint and Recovery Ingredients
    35/100

    Hyaluronic acid is a glycosaminoglycan found naturally in synovial fluid, skin and connective tissue. Oral supplements (usually sodium hyaluronate) are positioned for joint comfort and skin hydration.

    Joint-health formulasSkin hydration productsHealthy-ageing blends
    0 studies1trademarked versions
    View

    White Kidney Bean Extract

    Metabolic Health Ingredients
    35/100

    White kidney bean extract is standardised for alpha-amylase inhibiting activity (measured in AI units). It is marketed as a 'starch blocker' that reduces the digestion of complex carbohydrates.

    Carbohydrate-blocking supplementsWeight-management formulas
    0 studies1trademarked versions
    View

    Apple Fruit Extract

    General Health Ingredients
    20/100

    Apple fruit extract is standardised for polyphenols such as phloridzin, chlorogenic acid and quercetin glycosides. It is used as a general antioxidant ingredient rather than for any specific validated indication.

    Antioxidant blendsGeneral-health formulasPolyphenol supplements
    0 studies1trademarked versions
    View

    Bacopa Monnieri

    Nootropics
    45/100

    Bacopa monnieri is an Ayurvedic herb standardised for bacosides. It is one of the better-studied herbal nootropics, with several human trials suggesting benefits for memory acquisition and retention after weeks of consistent use.

    Memory and learning supplementsNootropic stacksStress-support formulas
    0 studies1trademarked versions
    View

    Boswellia Serrata

    Joint and Recovery Ingredients
    40/100

    Boswellia serrata resin is standardised for boswellic acids, particularly AKBA (3-O-acetyl-11-keto-beta-boswellic acid). Human trials, mostly in osteoarthritis, report modest improvements in joint pain and function.

    Joint-comfort formulasInflammation-balance supplementsCurcumin combination products
    0 studies2trademarked versions
    View

    Gotu Kola

    Botanical Extracts
    25/100

    Gotu kola (Centella asiatica) is standardised for triterpenes such as asiaticoside and madecassoside. Best known in skincare ('cica'), oral use is positioned for circulation, skin and traditional cognitive support; human evidence is limited.

    Skin and connective-tissue formulasCirculation supplementsTraditional cognitive support
    0 studies1trademarked versions
    View

    L-Selenomethionine

    Minerals
    50/100

    L-selenomethionine is the organic, amino-acid-bound form of selenium and the main form found in foods. It is absorbed efficiently and incorporated into body proteins, providing a slow-release selenium pool.

    Selenium repletionThyroid-support formulasAntioxidant-enzyme support
    0 studies1trademarked versions
    View

    Green Coffee Bean Extract

    Metabolic Health Ingredients
    30/100

    Green coffee bean extract is made from unroasted coffee beans and standardised for chlorogenic acids, which are largely destroyed by roasting. It is marketed for weight management and glycaemic support; human evidence is mixed and early meta-analyses were affected by a retracted trial.

    Weight-management formulasMetabolic-health blends
    0 studies1trademarked versions
    View

    Ginkgo Biloba

    Nootropics
    35/100

    Ginkgo biloba leaf extract, standardised to 24% flavone glycosides and 6% terpene lactones (the '24/6' standard), is one of the most studied herbal extracts. Large trials in healthy older adults have not shown prevention of cognitive decline; smaller studies suggest modest effects in existing impairment.

    Cognitive-support supplementsCirculation formulasHealthy-ageing products
    0 studies1trademarked versions
    View

    Citicoline

    Nootropics
    45/100

    Citicoline (CDP-choline) is a choline donor and uridine precursor that supports phosphatidylcholine synthesis in neuronal membranes. It has a substantial clinical history in stroke and cognitive impairment in some countries, and is a popular nootropic-stack ingredient.

    Nootropic stacksFocus and attention formulasBrain-health supplements
    0 studies1trademarked versions
    View

    Quercetin

    General Health Ingredients
    35/100

    Quercetin is a flavonol found in onions, apples and berries. Supplemental quercetin (often the dihydrate form) is positioned for immune support and antioxidant activity; oral bioavailability of the plain aglycone is low, driving interest in phytosome and glycoside forms.

    Antioxidant and immune-support formulasHealthy-ageing blendsAllergy-season supplements
    0 studies1trademarked versions
    View

    Ginger Extract

    Botanical Extracts
    45/100

    Ginger root extract, standardised for gingerols, is one of the best-supported botanicals for nausea — particularly pregnancy-related and motion sickness — with additional evidence for digestive comfort and modest anti-inflammatory effects.

    Digestive-comfort supplementsNausea reliefAnti-nausea and travel formulas
    0 studies1trademarked versions
    View

    Panax Ginseng

    Adaptogens
    35/100

    Panax ginseng root, standardised for ginsenosides, is a classic adaptogen used for fatigue, vitality and cognitive support. Human trials show modest, inconsistent benefits for fatigue and cognition; quality and ginsenoside content vary widely between products.

    Energy and vitality formulasAdaptogen blendsCognitive-support supplements
    0 studies1trademarked versions
    View

    Phosphatidylserine

    Nootropics
    40/100

    Phosphatidylserine is a phospholipid concentrated in neuronal membranes. Modern supplements are soy- or sunflower-derived (the original bovine cortex form is no longer used). Human studies suggest modest cognitive benefits in older adults and possible cortisol blunting during exercise stress.

    Cognitive-support formulasCortisol/stress-management supplementsSports nootropic blends
    0 studies1trademarked versions
    View

    Lutein

    General Health Ingredients
    50/100

    Lutein is a xanthophyll carotenoid concentrated in the macula of the eye, where it filters blue light and acts as an antioxidant. It is one of the better-supported eye-health nutrients, anchored by the AREDS2 trial for age-related macular degeneration (AMD) progression.

    Eye-health formulasBlue-light/screen-time supplementsHealthy-ageing products
    0 studies1trademarked versions
    View

    Lycopene

    General Health Ingredients
    35/100

    Lycopene is the red carotenoid of tomatoes, standardised in extracts (commonly 5–10%). It is positioned for prostate health, cardiovascular support and skin photoprotection; evidence is largely observational with some supportive small trials.

    Antioxidant formulasProstate-health supplementsSkin/UV-support products
    0 studies1trademarked versions
    View

    Bacillus Coagulans

    Digestive Enzymes, Probiotics & Fibers
    40/100

    Bacillus coagulans is a spore-forming probiotic whose spores survive heat and stomach acid far better than typical lactobacilli, making it practical for shelf-stable products. Strain-specific human trials support benefits for IBS-type symptoms and digestive comfort.

    Probiotic supplementsDigestive-comfort formulasProtein-digestion support blends
    0 studies1trademarked versions
    View

    Cayenne Extract

    Metabolic Health Ingredients
    35/100

    Cayenne extract is standardised for capsaicinoids, the compounds responsible for chilli heat. Capsaicin produces a measurable but small increase in energy expenditure and fat oxidation, and is a staple of thermogenic weight-management products.

    Thermogenic fat-burner formulasMetabolism-support supplements
    0 studies1trademarked versions
    View

    Triphala

    Botanical Extracts
    25/100

    Triphala is a traditional Ayurvedic blend of three fruits — amla (Emblica officinalis), bibhitaki (Terminalia bellirica) and haritaki (Terminalia chebula) — used primarily for digestive regularity. Modern human evidence is limited to a handful of small trials.

    Digestive-regularity supplementsAyurvedic formulasGut-health blends
    0 studies1trademarked versions
    View

    Soy Isoflavones

    Hormonal Support Ingredients
    40/100

    Soy isoflavones (genistein, daidzein, glycitein) are phytoestrogens standardised in extracts (commonly 40%). The best evidence supports modest reduction of menopausal hot flushes; effects on bone and cardiovascular markers are less consistent.

    Menopause-support formulasWomen's-health supplementsBone-health blends
    0 studies1trademarked versions
    View

    Green Tea Extract

    Metabolic Health Ingredients
    40/100

    Green tea extract is standardised for catechins, principally EGCG. It is one of the most common fat-burner ingredients: human trials show small increases in energy expenditure and fat oxidation, amplified by caffeine, with rare hepatotoxicity at high doses on an empty stomach.

    Fat-burner formulasAntioxidant supplementsMetabolism-support blends
    0 studies1trademarked versions
    View

    Serratiopeptidase

    Digestive Enzymes, Probiotics & Fibers
    20/100

    Serratiopeptidase (serrapeptase) is a proteolytic enzyme originally isolated from silkworm-gut bacteria. It is marketed as a 'systemic enzyme' for inflammation and recovery, but the human evidence base is thin and oral absorption of an intact enzyme is physiologically uncertain.

    Systemic-enzyme supplementsRecovery and inflammation-balance formulas
    0 studies1trademarked versions
    View