Apple Fruit Extract
Also known as: Apple polyphenols, Malus domestica extract, Applephenon
Apple polyphenols are a mixed class of flavonoids and phenolic acids with antioxidant activity in vitro. Human data are sparse and mostly relate to whole-apple consumption rather than concentrated extracts.
Last reviewed: 2026-10-06 · 0 indexed studies
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Overview
Apple fruit extract is standardised for polyphenols such as phloridzin, chlorogenic acid and quercetin glycosides. It is used as a general antioxidant ingredient rather than for any specific validated indication.
Mechanism & Function
Mechanism of Action
Proposed actions include free-radical scavenging, modest inhibition of carbohydrate-digesting enzymes (phloridzin inhibits SGLT1), and general polyphenol effects on endothelial function — mostly demonstrated in vitro or in animals.
Physiological Role
No physiological role; a source of dietary polyphenols.
Primary Pathways
Performance / Health Relevance
No established performance relevance.
Evidence Review
No human clinical studies indexed for this ingredient yet.
No meta-analyses or systematic reviews indexed for this ingredient yet.
Dimensions marked N/A have no indexed evidence of that class. They are shown as unavailable rather than scored.
Practical Use & Dosage
- Minimum Effective Dose
- Not established
- Optimal Range
- Not established; products typically provide 100–600 mg/day
- Upper / Caution Level
- Not well defined
- Timing
- Daily
- Best Format
- Standardised polyphenol extract
- Bioavailability
- Apple polyphenols have moderate-to-low bioavailability, typical of the flavonoid class.
- Absorption Considerations
- Glycoside forms are hydrolysed in the gut before absorption.
Safety & Interactions
Side Effects
- •None commonly reported at supplemental doses
Contraindications
- Apple allergy
Drug Interactions
- •None well established
Who Should Avoid
- •People with apple allergy
Monitoring
None routinely.
Frequently Asked Questions
Auto-generated from indexed evidence — dosage, safety, interactions, and more.
When is Apple Fruit Extract typically used or indicated?
Apple Fruit Extract is most commonly used for: Antioxidant blends, General-health formulas, Polyphenol supplements. No physiological role; a source of dietary polyphenols.
How does Apple Fruit Extract work?
Proposed actions include free-radical scavenging, modest inhibition of carbohydrate-digesting enzymes (phloridzin inhibits SGLT1), and general polyphenol effects on endothelial function — mostly demonstrated in vitro or in animals.
What is the recommended dose of Apple Fruit Extract?
The optimal range is Not established; products typically provide 100–600 mg/day. with a minimum effective dose of Not established. Best taken: Daily. Upper / caution level: Not well defined.
What are the side effects of Apple Fruit Extract?
Reported side effects include: None commonly reported at supplemental doses. Monitoring: None routinely.
Does Apple Fruit Extract interact with medications?
Known or theoretical interactions: None well established. Always check with a clinician before combining with prescription medication.
Who should avoid Apple Fruit Extract?
Apple Fruit Extract is generally not recommended for: People with apple allergy; and Apple allergy.
How strong is the evidence for Apple Fruit Extract?
Evidence level: Preliminary (overall score 20/100), based on 0 indexed studies on SuppIndex.
Research & References (0)
No studies match this filter
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Research Overview
Preliminary EvidenceCite this ingredient
One-click citation export in APA, MLA, Chicago, BibTeX, or HTML. The URL below is stable and safe to link.
Stable URL
https://thesuppindex.com/ingredients/apple-fruit-extract
SuppIndex. (2026). Apple Fruit Extract: Evidence summary, dosage and clinical studies. Retrieved October 16, 2026, from https://thesuppindex.com/ingredients/apple-fruit-extract
Based on 0 indexed studies · Evidence level: Preliminary.
Goal Ratings
Stack Compatibility
Appears in mixed polyphenol and antioxidant blends.