Ingredient Database

Agmatine Sulfate is a metabolite of L-arginine produced by decarboxylation via arginine decarboxylase (ADC). It functions as a neuromodulator and NO regulator with a unique mechanism — it inhibits the arginase enzyme that breaks down arginine, thereby extending the half-life of circulating arginine and prolonging NO-mediated vasodilation. It also acts on imidazoline, alpha-2 adrenergic, and NMDA receptors for neuroprotective and mood-regulating effects.