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    Botanical ExtractsNatural

    AstraGin

    Also known as: Astragalus + Panax notoginseng extract, AstraGin

    Standardised botanical blend that upregulates intestinal transporter expression and supports gut epithelium recovery.

    Last reviewed: 2026-06-23 · 1 indexed study

    Evidence Score
    56/100
    Nutrient absorption enhancerGut health
    Data Completeness3/4 · 75%
    Evidence ScoreDosageSafetyLinked Studies

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    Overview

    AstraGin is a patented blend of Astragalus membranaceus and Panax notoginseng extracts shown to upregulate intestinal transporters (SGLT1, GLUT-4, CAT-1) and enhance amino acid, glucose, and vitamin absorption.

    Mechanism & Function

    Mechanism of Action

    Increases intestinal expression of nutrient transporters, supports tight junction integrity, and modulates inflammatory signalling in the gut.

    Physiological Role

    Used as a 'bioenhancer' in pre-workouts and amino-acid formulas to improve uptake of citrulline, arginine, BCAAs, and other actives.

    Primary Pathways

    Intestinal SGLT1/GLUT-4/CAT-1 upregulationTight junction integrityGut anti-inflammatory action

    Performance / Health Relevance

    Manufacturer-supported in vitro and animal data; human RCTs limited but consistent.

    Evidence Review

    Overall56/100
    Human ClinicalN/A

    No human clinical studies indexed for this ingredient yet.

    Meta-AnalysisN/A

    No meta-analyses or systematic reviews indexed for this ingredient yet.

    Mechanistic72/100
    Real-World58/100
    Safety86/100

    Dimensions marked N/A have no indexed evidence of that class. They are shown as unavailable rather than scored.

    Practical Use & Dosage

    Minimum Effective Dose
    25 mg
    Optimal Range
    25–50 mg per dose with target nutrients
    Upper / Caution Level
    ~100 mg/day
    Timing
    With nutrients to enhance
    Best Format
    Capsule, powder
    Bioavailability
    Active in vivo at low doses.
    Absorption Considerations
    Acts in gut lumen on transporter expression.

    Safety & Interactions

    Side Effects

    • •Generally well tolerated

    Contraindications

    • Autoimmune disease (theoretical)

    Drug Interactions

    • •Immunosuppressants
    • •Diabetes meds (theoretical)

    Who Should Avoid

    • •Pregnancy
    • •Active infection

    Monitoring

    None routine.

    Frequently Asked Questions

    Auto-generated from indexed evidence — dosage, safety, interactions, and more.

    When is AstraGin typically used or indicated?

    AstraGin is most commonly used for: Nutrient absorption enhancer, Gut health. Used as a 'bioenhancer' in pre-workouts and amino-acid formulas to improve uptake of citrulline, arginine, BCAAs, and other actives.

    How does AstraGin work?

    Increases intestinal expression of nutrient transporters, supports tight junction integrity, and modulates inflammatory signalling in the gut.

    What is the recommended dose of AstraGin?

    The optimal range is 25–50 mg per dose with target nutrients. with a minimum effective dose of 25 mg. Best taken: With nutrients to enhance. Upper / caution level: ~100 mg/day.

    What are the side effects of AstraGin?

    Reported side effects include: Generally well tolerated. Monitoring: None routine.

    Does AstraGin interact with medications?

    Known or theoretical interactions: Immunosuppressants; and Diabetes meds (theoretical). Always check with a clinician before combining with prescription medication.

    Who should avoid AstraGin?

    AstraGin is generally not recommended for: Pregnancy; Active infection; and Autoimmune disease (theoretical).

    How strong is the evidence for AstraGin?

    Evidence level: Moderate (overall score 56/100), based on 1 indexed study on SuppIndex.

    Research & References (1)

    AstraGin on amino acid and glucose absorption

    In Vitro2015Low

    Significant upregulation of SGLT1, GLUT-4, CAT-1; improved amino acid uptake.

    Trademark Ingredients

    AstraGin®

    Manufacturer:

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    Research Overview

    Moderate Evidence
    1Total Studies
    0Human Trials
    0Meta-Analyses
    2015Latest Study
    1Animal / In Vitro
    0Athlete Studies
    Primary data sourceIn Vitro
    Pooled evidence (meta-analysis / systematic review)No

    Cite this ingredient

    One-click citation export in APA, MLA, Chicago, BibTeX, or HTML. The URL below is stable and safe to link.

    Stable URL

    https://thesuppindex.com/ingredients/astragin

    SuppIndex. (2026). AstraGin: Evidence summary, dosage and clinical studies. Retrieved October 16, 2026, from https://thesuppindex.com/ingredients/astragin

    Based on 1 indexed studies · Evidence level: Moderate.

    Goal Ratings

    Recovery
    General Health
    Endurance

    Stack Compatibility

    Common in amino acid, pre-workout, and absorption-focused stacks.

    L-CitrullineArginineBCAAs